Casos y artículos

Stem cell therapy for spine and orthopedic problems

Soft tissue injuries, cranial cruciate ligament disease (CCLD), degenerative disc diseases and osteoarthritis are common conditions in dogs and cats. These injuries are due to the forces placed on the joints and are more common because of the repetitive injuries and microtrauma to tendons, ligaments, and articular surfaces. The degenerative arthritic changes progress throughout your dog’s life.Most therapies treat symptoms or may slow the progression of osteoarthritis. Stem cell therapy treats symptoms, slows the disease, decreases pain and consumption of pain medications, and repairs some or most of the damaged tissue. It will improve your pet’s quality of life.
Since the 1960s and the therapeutic use of hematopoietic stem cells of bone marrow origin, there has been an increasing interest in the study of undifferentiated progenitors that have the ability to proliferate and differentiate into various tissues. Stem cells (SC) with different potency can be isolated and characterised. Despite the promise of embryonic stem cells, in many cases, adult or even fetal stem cells provide a more interesting approach for clinical applications. It is undeniable that mesenchymal stem cells (MSC) from bone marrow, adipose tissue, or Wharton’s Jelly are of potential interest for clinical applications in regenerative medicine because they are easily available without ethical problems for their uses. During the last 10 years, these multipotent cells have generated considerable interest and have particularly been shown to escape to allogeneic immune response and be capable of immunomodulatory activity. These properties may be of a great interest for regenerative medicine. Different clinical applications are under study (cardiac insufficiency, atherosclerosis, stroke, bone and cartilage deterioration, diabetes, urology, liver, ophthalmology, and organ’s reconstruction). This review focuses mainly on tissue and organ regeneration using stem cells.

A stem cell is characterized by its ability to divide and create another cell like itself and by its potential to become many different types of cells. There are two broad types of stem cells:
Embryonic stem cells – Found in a developing embryo, embryonic stem cells are intended to form a whole animal or organ and have unlimited potential of development into any type of tissue. In human medicine, ethical and legal debates surround the use of embryonic stem cells for research and therapy; such controversy does not exist with the use of adult stem cells.
Adult stem cells – Found in most adult tissues, adult stem cells act as a repair system for the body, replenishing specialized cells and maintaining the normal turnover of regenerative organs, such blood, skin, or cartilage. Adult stem cells are also multi-potent, meaning the cells have the potential to differentiate themselves to become various types of cells.
Unlike the stem cell therapy that has been used in human medicine for many years – newer technology uses only adult stem cells harvested from the pet’s own body. This means no fetal cells are involved so no ethical or moral values are at stake. It’s a completely natural therapy – just the body healing itself with a little help from modern technology. It has been discovered that “dormant” stem cells are found in large quantities in body fat.

Autologous (tissues from the patient’s body) stem cell treatment has shown excellent safety in the thousands of animals treated. No major adverse reactions have been reported; the most “severe” reported reaction is local inflammation, or discomfort at the injection site.
Spine, Disc Disease
Cranial Cruciate Ligament Disease (CCLD)
Arthritis, Osteoarthritis
Orthopedic Soft Tissue Damage – Joint Injuries
Orthopedic Soft Tissue Damage – Ligaments Injuries
Orthopedic Soft Tissue Damage – Cartilage Injuries
Orthopedic Soft Tissue Damage – Tendons Injuries

Stem Cell therapy is not a “cure-all” for all bone and soft tissue damage. Results between individual cases will vary. Its effectiveness as a therapy has only been highlighted through thousands of reports on pets having undergone the procedure. However, with proper Canine Rehabilitation done, the chances of restoring the quality of life in your pet is above average. We can only rely on the data obtained through documented case studies to support the procedure. An old dog with arthritis can’t become a puppy again, but we hope to reduce the pain and inflammation caused by the disease, thereby providing better quality of life. We also expect greater mobility and less reliance on medications after the procedure.